Early Prediction of Adolescent Depression (EPAD)

 
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Overview

Aims
The Early Prediction of Adolescent Depression (EPAD) Study is a prospective, longitudinal cohort of recurrently depressed parents and their offspring. By tracking families over a decade and documenting their experiences, the study offers in-depth insights into the causes, impacts and resilience factors related to depression. This insight is used to develop evidence-based early intervention and support strategies, as well as to create predictive tools for mental health to ensure targeted support for those most in need. Overall, the study aims to inform national and international understanding and to support affected individuals and their families.

The EPAD Study is also known as the Cardiff University Mood and Wellbeing Study.

Institution
Cardiff University

Geographic coverage - Nations
Wales

Geographic coverage - Regions
Nationwide

Start date
2007

Catalogue record last updated
25/09/2024

Sample

Sample type
Cohort study

Sample details
Families were mainly recruited from general practices in South Wales. Parents were screened over the telephone to confirm they met eligibility criteria for the study at the time of initial recruitment: had a history of at least two prior episodes of major depressive disorder and a biologically related child aged 9-17 years living at home with them. In cases where a parent had two eligible children, the youngest was selected to participate. Families were excluded if the child had a moderate to severe learning disability (IQ less than 50) or if the parent had bipolar disorder or a psychotic disorder at baseline.

Sample size at recruitment
337 families

Sample size at most recent sweep
197 families

Sex
All

Age at recruitment
9-17 years

Cohort year of birth
Varied

Data

Data access
Contact study team to express an interest in accessing the data
www.cardiff.ac.uk/research/explore/find-a-project/view/the-cardiff-university-mood-and-wellbeing-study

Genetic data collected

Linkage to administrative data

Additional information

Website
www.cardiff.ac.uk/research/explore/find-a-project/view/the-cardiff-university-mood-and-wellbeing-study

Notes
Also known as the Cardiff University Mood and Wellbeing Study

Related themes
Diet and nutrition, Education, Loneliness and social isolation, Neighbourhood, Parenting and family, Political and social attitudes, Sleep problems, Socioeconomic status and deprivation, Victimisation and life events, Work and employment

Summary
The EPAD Study follows children between the ages of 9-17 years who are related to and living with parents with a history of depression. The study explores why and how young people develop mental health issues to find ways to predict the onset of issues as well as to create helpful interventions and support strategies that will help alleviate them.

Key Papers

Mental health resilience in the adolescent offspring of parents with depression: a prospective longitudinal study
doi.org/10.1016/S2215-0366(15)00358-2

Funders
Sir Jules Thorn Charitable Trust
Economic and Social Research Council
Medical Research Council
Mental health measures timeline

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