Whitehall II

 
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Overview

Aims
The Whitehall II study was established to investigate the causes of social inequalities in health with a cohort of 10,308 participants was recruited from the British Civil Service in 1985. The study has shown the importance of psychosocial factors such as work stress and work-family conflict in heart disease and diabetes in addition to the contribution of unhealthy behaviours and traditional risk factors such as high blood pressure. The study is now a study on ageing, with the 35-year follow-up allowing research on multimorbidity, functional decline, frailty, disability, and dementia.

Institution
UCL Brain Science, University College London

Geographic coverage - Nations
England

Geographic coverage - Regions
London

Start date
1985

Catalogue record last updated
28/03/2024

Sample

Sample type
Occupational cohort; Ageing cohort

Sample details
The target population for the Whitehall II study was all civil servants aged 35–55 years working in the London offices of 20 Whitehall departments in 1985–88. Members of the target population were invited to participate by letter. The achieved sample size was 10,308 people; 3413 women and 6895 men. The participants, who were from clerical and office support grades, middle-ranking executive grades, and senior administrative grades, differ widely in salary. Some have remained in the civil service. Many have retired, and others have taken employment elsewhere; some are unemployed. For more details see Marmot & Brunner 2005.

Sample size at recruitment
10,308

Sample size at most recent sweep
4,307 (2022 - Phase 13)

Sex
All

Age at recruitment
35-55 years

Cohort year of birth
1930-53

Data

Data access
Data request - Dementias Platform UK
portal.dementiasplatform.uk/Apply

Genetic data collected

Linkage to administrative data
Education data
Environmental data
Health data

Additional information

Website
ucl.ac.uk/epidemiology-health-care/research/epidemiology-and-public-health/research/whitehall-ii

Notes
Also known as the Stress and Health Study

Related themes
Biomarkers, Cognitive measures, Cognitive decline, Diet and nutrition, Housing, Socioeconomic status and deprivation, Loneliness and social isolation, Neighbourhood, Physical health assessment, Digital technology and social media, Victimisation and life events, Reproductive health, Work and employment, Parenting and family, Sleep problems, Social care - receipt, Social care - provision, Social care - need

Summary
Whitehall II follows civil servants between the ages of 35-55 working in the London offices of 20 Whitehall departments. The study aims to understand the causes of social inequalities in health.

Key Papers

Cohort Profile: The Whitehall II Study.
doi.org/10.1093/ije/dyh372

Funders
Medical Research Council
British Heart Foundation
National Institute on Aging
Economic and Social Research Council
European Union
European Research Council

National Heart, Lung & Blood Institute
Mental health measures timeline

Sweep name:

Cohort member age:

Data collection period:

Notes:

Physical health measures:

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